个人简历

1. 个人综述

• 介绍：姓名，朱鸿亮，在中国农业大学食品科学与营养工程学院担任教授、副院长，主要研究方向为果蔬采后生理与分子生物学、果实发育和成熟机制，从事果蔬品质调控方面的教学和科研工作。

2. 个人背景与教育经历

• 出生年月：1980年9月，内蒙古
• 教育背景：
  • 1999.09-2003.07，中国农业大学，获学士学位。
  • 2003.09-2008.07，中国农业大学，获工学博士学位。
  • 2008.08-2010.01，美国得州理工大学，博士后。
  • 2010.02-2013.01，美国得州农工大学，博士后。
• 工作履历：
  • 2013.04至今，中国农业大学食品科学与营养工程学院，教授。

3. 研究方向与技术领域

• 研究方向：果蔬采后生理与分子生物学，果蔬营养物质代谢调控，果实发育和成熟机制。
• 技术热词：CRISPR/Cas9技术，基因编辑，长非编码RNA（lncRNA），果实发育和成熟机制，果蔬采后生理与分子生物学，果蔬营养物质代谢调控。

4. 主要学术成果与贡献

• 研究成果综述
  • 以第一作者或通讯作者在Cell、Nature Structural & Molecular Biology、Plant Cell、New Phytologist、Plant Physiology、Plant Biotechnology Journal、Plant Journal、Horticulture Research等多个国际著名期刊上发表学术论文15篇。
  • 先后主持国家优秀青年科学基金项目1项、国际（地区）合作与交流项目1项、重大研究计划培育项目1项、面上项目4项。
• 代表性论文：
  • Yu, Tzeng, Li, Chen, Zhong, Fu, Zhu, Luo, Zhu. Genome-wide identification of long non-coding RNA targets of the tomato MADS box transcription factor RIN and functional analysis, Horticulture Research, 2019, 6:77.
  • Wang, Deng, Zhang, Wang, Wang, Liu, Liu, Xu, Li, Fu, Zhu, Luo, Zhu. Tomato DCL2b is required for the biogenesis of 22-nt small RNAs, the resulting secondary siRNAs, and the host defense against ToMV, Horticulture Research, 2018, 5:62.
  • Li, Fu, Zhu, Luo, Zhu. CRISPR/Cas9-mediated mutagenesis of lncRNA1459 alters tomato fruit ripening, The Plant Journal, 2018, 94:513-524.
  • Li, Wang, Chen, Tian, Fu, Zhu, Luo, Zhu. Lycopene is enriched in tomato fruit by CRISPR/Cas9-mediated multiplex genome editing, Frontiers in Plant Science, 2018, 9:559.
  • Li, Li, Li, Fu, Zhu, Tian, Luo, Zhu. Multiplexed CRISPR/Cas9-mediated metabolic engineering of γ-aminobutryic acid levels in Solanum lycopersicum, Plant Biotechnology Journal, 2018, 16:415-427.
  • Yang, Zhu, Li, Yan, Fu, Zhu, Tian, Luo, Zhu. The RNA editing factor SlORRM4 is required for normal fruit ripening in tomato, Plant Physiology, 2017, 175:1690-1702.
  • Li, Zhu, Luo. Understanding the functions of long non-coding RNAs through their higher-order structures, International Journal of Molecular Sciences, 2016, 17(5):702.
  • Zhu, Yang, Li, Fu, Wen, Luo, Zhu. RNA sequencing and functional analysis implicate the regulatory role of long non-coding RNAs in tomato fruit ripening, Journal of Experiment Botany, 2015, 66:4483-4495.
  • Gao, Ju, Cao, Zhai, Qin, Zhu, Fu, Luo, Zhu. MicroRNA profiling analysis throughout tomato fruit development and ripening reveals potential regulatory role of RIN on microRNAs accumulation, Plant Biotechnology Journal, 2015, 13:370-382.
  • Li, Yang, Zeng, Qu, Fu, Zhu, Luo, Ostersetzer-Biran, Zhu. Glycine-rich RNA-binding cofactor RZ1AL is associated with tomato ripening and development, Horticulture Research, 2022, 9:uhac134.
  • Ma, Yang, Wang, Cheng, Zhou, Li, Zhang, Li, Zhang, Wang, Zeng, Gong, Zhu, Deng, Qu, Zhu, Fu, Luo, Zhu. SlRBP1 promotes translational efficiency via SleIF4A2 to maintain chloroplast function in tomato, The Plant Cell, 2022, 34(7):2747–2764.
  • Zhu, Zhu. Modified Gene Editing Systems: Diverse Bioengineering Tools and Crop Improvement, Frontiers in Plant Science, 2022, 13:847169.
  • Deng, Ma, Zhang, Zhu. Small RNAs Participate in Plant-Virus Interaction and Their Application in Plant Viral Defense, International Journal of Molecular Sciences, 2022, 23(2):696.
  • Sun, Zang, Zhou, Song, Chen, Zhang, Liu, Yi, Zhu, Fu, Zhu, Qu. A tomato receptor-like cytoplasmic kinase, SlZRK1, acts as a negative regulator in wound-induced jasmonic acid accumulation and insect resistance, Journal of Experimental Botany, 2021, 72(20):7285–7300.
  • Ma, Cheng, Li, Deng, Zhang, Zhu. Roles of Plant Glycine-Rich RNA-Binding Proteins in Development and Stress Responses, International Journal of Molecular Sciences, 2021, 22(11):5849.
  • Wang, Zhang, Zhang, Zhu. CRISPR/Cas9-Mediated Gene Editing Revolutionizes the Improvement of Horticulture Food Crops, Journal of Agricultural and Food Chemistry, 2021, 69(45):13260–13269.
  • Gao, Wei, Fan, Zhao, Zhang, Jing, Zhu, Zhu, Shan, Chen, Grierson, Luo, Jemrić, Jiang, Fu. Re-evaluation of the nor mutation and the role of the NAC-NOR transcription factor in tomato fruit ripening, Journal of Experimental Botany, 2020, 71(12):3759.
  • Yang, Liu, Wang, Li, Zhu, Ren, Deng, Zhu, Fu, Qu, Luo, Zhu. Molecular and functional diversity of organelle RNA editing mediated by RNA recognition motif-containing protein ORRM4 in tomato, The New Phytologist, 2020, 228(2):570–585.
  • Wang, Zhang, Zhu. CRISPR technology is revolutionizing the improvement of tomato and other fruit crops, Horticulture Research, 2019, 6:77.
  • Yu, Tzeng, Li, Chen, Zhong, Fu, Zhu, Luo, Zhu. Genome-wide identification of long non-coding RNA targets of the tomato MADS box transcription factor RIN and function analysis, Annals of Botany, 2019, 123(3):469–482.

5. 学术荣誉与社会兼职

• 社会职务及任期：
  • 中国园艺学会釆后科学与技术分会，秘书长。
  • 中国园艺学会青年分会，常务理事。
  • 中国植物生理与植物分子生物学学会开花成熟衰老专业委员会，委员。
  • 美国-以色列BARD项目和新加坡SFS项目，评委。
  • Nature Food、Biotechnology Advance、New Phytologist和Plant Biotechnology Journal等，期刊审稿人。

6. 团队建设与人才培养

• 研究生团队专注于果蔬采后生理与分子生物学、果实发育和成熟机制等领域。
• 指导的学生在《Cell》、《Nature Structural & Molecular Biology》、《Plant Cell》、《New Phytologist》、《Plant Physiology》、《Plant Biotechnology Journal》、《Plant Journal》、《Horticulture Research》等国际著名期刊上发表了多篇学术论文。

7. 科技成果转化与产业应用

• 研究成果在果蔬产业中得到应用。
• 曾代表中国农业大学食品科学与营养工程学院与大同云州区政府签订战略合作协议。
• 积极参与多项产学研项目。